Transcriptomics New tech always has risks and limitations, single-cell and spatial transcriptomics are no exception Single-Cell and Spatial Transcriptomics: Risks, Limitations, and Questions to Ask
Historical Paper Review A wormy discovery becomes a knockout laboratory technique One of the best ways to figure out what a gene does is to get rid of it and see what happens.
Historical Paper Review Linus Pauling molecularly characterized the first Mendelian Disease: Sickle Cell Anemia Sickle Cell Anemia was the first inherited disease to be molecularly characterized. It was done in 1949 using a revolutionary new method: electrophoresis.
Paid-members only Molecular Testing At-home testing companies were put on notice with FDA's most recent warning letter to Molecular Testing Labs
Genomic Sequencing Everything you ever wanted to know about cluster based and single-molecule sequencing Clusters vs single molecules in DNA sequencing: Here’s the short and the long of it.
DNA FFPE is great for histology and terrible for molecular testing Formalin-fixed, paraffin-embedded (FFPE) tissues in oncology diagnostics: is there a better way?