DNA The structure of the DNA double-helix was published in 1953, but it took another 13 years to actually crack the genetic code. The questions of how DNA is copied and codes for proteins remained for a while after the structure was confirmed.
DNA Chargaff’s Rule is the most basic rule of DNA A and T, and G and C are present in the same amounts in DNA. It’s the most basic rule of DNA. It’s also called Chargaff’s Rule.
DNA Deoxyribonucleic acid (DNA) is the genetic material, but early on, most of science thought the genetic material was protein —that changed in 1952 Deoxyribonucleic acid (DNA) is the genetic material, but early on, most of science thought the genetic material was protein. That changed in 1952.
Genomic Sequencing Commercial industrial engineering is the savior of high-throughput genomics We ‘completed’ the human genome in 2003, thanks mostly to commercial industrial engineering.
Genetics 6LL3, better known as Dolly the Sheep, showed that mammalian cloning was possible in 1997 Why was a sheep the first choice for this ground-breaking work?
DNA One of the most important papers in the history of genetics was basically ignored when it was published in 1944 When Oswald Avery, Colin Macleod and Maclyn McCarty published their paper in 1944 showing unequivocally that DNA was the genetic material, it wasn’t very well received.
Genetics Beadle and Tatum were the first to marry biochemistry with genetics in 1941 The field of molecular biology was born in 1941 through the marriage of genetics and biochemistry.
Genomics RNA interference was a knockout discovery in 1998! One of the best ways to figure out what a gene does is to get rid of it and see what happens.
Proteomics Fred Sanger, the father of DNA sequencing, cut his teeth doing protein sequencing and snagged a Nobel in the process! Fred Sanger received a Nobel Prize for his work with Insulin. As the father of DNA sequencing, this surely was for insulin's nucleic acid sequence? It wasn't.
DNA The "most beautiful experiment in biology" was performed by Meselson and Stahl in 1957 Watson and Crick solved the structure of DNA and everyone lived happily ever after, right? Wrong. That was just the opening argument.
DNA The discovery of the DNA double-helix was the culmination of decades of work from numerous contributors History is written by victors, and that statement couldn't be more true than it is in the case of Watson and Crick's 'discovery' of the DNA double helix.
DNA Linus Pauling proposed a triple helical structure for DNA in 1953. Here's why he got it so wrong The kaleidoscopic image below is the triple helix Linus Pauling proposed as the structure of DNA in February 1953. Here's why he got it so wrong:
DNA Florence Bell and William Astbury's x-ray diffraction work on a 'pile of pennies' The first crystal structure of DNA was published in 1938. It was generated by Florence Bell, a scientist you need to know.
DNA The story of Phoebus Levene, one of the mostly invisible grandfathers of nucleic acids Watson and Crick were the first to describe the structure of the DNA double helix. Their major contribution to science was, at its core, a synthesis of all of the best data available at the time.
DNA The story of the polymerase chain reaction and how sometimes timing is everything The method below has been cited more than 600,000 times and is one of the most important developments in the history of science.
Genomics The story of how Solexa and Illumina combined forces to revolutionize the field of genomics Illumina is considered by many to have single handedly transformed the field of genomics. They did it by building on the foundation Solexa established in 1997.
DNA A multi-billion dollar industry was spawned from the discovery of circulating free DNA Two gels spawned a multi-billion dollar industry that didn't exist prior to their publication in 1997.
DNA The story of Rosalind Franklin and photo 51 The most famous photo in the history of genetics wasn’t generated by Watson and Crick, but that didn’t stop them from using it to solve the structure of DNA!
