Historical Paper Review Linus Pauling molecularly characterized the first Mendelian Disease: Sickle Cell Anemia Sickle Cell Anemia was the first inherited disease to be molecularly characterized. It was done in 1949 using a revolutionary new method: electrophoresis.
Genetics Ethnic Stratification: Sounds complicated, but in genomics it helps everyone Ethnic stratification and why single reference based analysis methods aren't 'good enough.'
Genetics A genetic investigation into the 'population collapse' at Easter Island What caused the 'collapse' of the Rapanui population on Easter Island? Genetics is now setting the record straight.
Genomics Pangenomes are here to bring equity to genomics Reference genomes: what they are and why the next big thing in genomics is the human pangenome.
Genetics The genetics of child sacrifice at Chichén Itzá Ritual human sacrifice was an important part of ancient Mayan life and now genetics is helping us to identify the origins of those who were sacrificed.
Genetics Would you like some Hi-C with that Woolly Mammoth? Woolly Mammoths were just big, furry, elephants, right? Maybe, and now we have the tools to compare the structures of their genomes.
Paid-members only Start-Upomics The 23andMe board tells Anne Wojcicki to do better in her attempt to take 23andMe private after a rocky 3 years as a public company
Genetics If only Ponce de Leon had known about IL-11 Who knew that the fountain of youth was as simple as blocking inflammatory signaling through IL-11?
Genetics Genealogy databases aren't just for finding your relatives anymore The killer app for consumer genetics literally is to catch killers. Here's why:
Genetics The 'Histone Code' fundamentally changed how we think about gene expression Histones were once thought to just be dumb structural proteins that held chromatin together; now we know that the ‘histone code’ is a major regulator of gene expression.
Autoimmunity A new genetic cause for Inflammatory Bowel Disease has been discovered Inflammatory diseases affect 5% of the population but we have a poor understanding of how to treat them. Multi-omic studies are changing that.
Evolution Have you ever wanted a superpower? Me too! Some human populations have genes that would make even Poseidon jealous!
Genetics The ends of our chromosomes are a paradox What if I told you that we didn't fully understand how human DNA was copied until 1989?
Genetics Biologically female mammals have two X chromosomes, but what might surprise you is that one of those X's is turned off. We first discovered there was something funny going on with X-chromosomes in 1948.
Multi-Omics Genetic Determinism: What it is and how we can avoid it with multi-omics One thing we constantly battle in genomics is, “What does it all mean?”
Genetics Barbara McClintock discovered a little thing called the transposable element in 1950 While everyone else was distracted by the structure of DNA, Barbara McClintock was discovering a little thing called the transposable element.
Paid-members only Genetics What happens if insurance companies start using your genetic data against you?
Genomics The evolutionary history of coffee is probably more complicated than you think That dark and delicious brew billowing clouds of irresistible coffee incense next to you is most likely the product of Coffea arabica.
Genetics The first human "Mendelian" disease was described in 1902 Mendel first described his laws of genetic inheritance in 1865. They were promptly ignored for 35 years.
Genetics Genetic code expansion and how we get to designer proteins Genetic code expansion might be the coolest thing in Omics that you've never heard of.
Genetics 6LL3, better known as Dolly the Sheep, showed that mammalian cloning was possible in 1997 Why was a sheep the first choice for this ground-breaking work?
Genetics Beadle and Tatum were the first to marry biochemistry with genetics in 1941 The field of molecular biology was born in 1941 through the marriage of genetics and biochemistry.
