Epigenetics There are lots of tools for probing the epigenome If epigenetics is the study of modifications that aren't coded in the DNA, how can we use DNA sequencing to learn anything about the epigenome?
Epigenetics Epigenetics! You've heard of it, but what do you know about it? There are lots of ‘omes: There's the genome, transcriptome, proteome, and metabolome - but the one above them all is the epigenome.
Artificial Intelligence A USB drive? Nah, an epigenetic drive! DNA data storage is coming for all of your bits (but now with an epigenetic spin)!
DNA Featured What came first, DNA methylation or the variant? DNA sequence variants can change more than just the properties of the proteins that genes code for, they can also change what proteins get expressed!
High-Throughput Sequencing In 2009, high throughput sequencing gave us our first glimpse of the 3-D organization of the DNA in our nuclei While chromosomes are usually depicted as X's, they actually spend most of their time jumbled up like a giant ball of yarn.
Genetics The 'Histone Code' fundamentally changed how we think about gene expression Histones were once thought to just be dumb structural proteins that held chromatin together; now we know that the ‘histone code’ is a major regulator of gene expression.