DNA - Omic.ly (Page 2)

Sign in Subscribe

DNA

A collection of 53 posts

Reverse Translation doesn't exist in nature, but that's not stopping us from trying to do it!

Protein Sequencing

Reverse Translation doesn't exist in nature, but that's not stopping us from trying to do it!

There are few things deserving of the superlative ‘holy grail,’ but Reverse Translation is one of them.

The Lac Operon: Everyone's heard of it, but do you know how it was discovered?

The Lac Operon: Everyone's heard of it, but do you know how it was discovered?

'If gene expression determines the function of a cell, it must be important to control that process?' Yes, very! Let me tell you about the PaJaMo experiment.

One of the most underappreciated techniques in Omics is Hi-C. That needs to change

Paid-members only

One of the most underappreciated techniques in Omics is Hi-C. That needs to change

In 2009, high throughput sequencing gave us our first glimpse of the 3-D organization of the DNA in our nuclei

High-Throughput Sequencing

In 2009, high throughput sequencing gave us our first glimpse of the 3-D organization of the DNA in our nuclei

While chromosomes are usually depicted as X's, they actually spend most of their time jumbled up like a giant ball of yarn.

Genealogy databases aren't just for finding your relatives anymore

Genealogy databases aren't just for finding your relatives anymore

The killer app for consumer genetics literally is to catch killers. Here's why:

The 'Histone Code' fundamentally changed how we think about gene expression

The 'Histone Code' fundamentally changed how we think about gene expression

Histones were once thought to just be dumb structural proteins that held chromatin together; now we know that the ‘histone code’ is a major regulator of gene expression.

If you thought the sequencing wars were hot already, have you considered what a $10 genome might do to them?

Paid-members only

High-Throughput Sequencing

If you thought the sequencing wars were hot already, have you considered what a $10 genome might do to them?

The 2-D structure of tRNA was solved in 1965, its solver probably isn't someone you've heard of before

The 2-D structure of tRNA was solved in 1965, its solver probably isn't someone you've heard of before

The next great mystery to solve after the discovery of the DNA double helix was to figure out how the nucleotide sequence coded for proteins.

The ends of our chromosomes are a paradox

The ends of our chromosomes are a paradox

What if I told you that we didn't fully understand how human DNA was copied until 1989?

Nettie Stevens, a former school teacher turned geneticist, discovered sex chromosomes in 1905. Here's her story:

Nettie Stevens, a former school teacher turned geneticist, discovered sex chromosomes in 1905. Here's her story:

Nettie Stevens’ contributions to the field of genetics were groundbreaking.

The structure of the DNA double-helix was published in 1953, but it took another 13 years to actually crack the genetic code.

The structure of the DNA double-helix was published in 1953, but it took another 13 years to actually crack the genetic code.

The questions of how DNA is copied and codes for proteins remained for a while after the structure was confirmed.

Chargaff’s Rule is the most basic rule of DNA

Chargaff’s Rule is the most basic rule of DNA

A and T, and G and C are present in the same amounts in DNA. It’s the most basic rule of DNA. It’s also called Chargaff’s Rule.

Deoxyribonucleic acid (DNA) is the genetic material, but early on, most of science thought the genetic material was protein —that changed in 1952

Deoxyribonucleic acid (DNA) is the genetic material, but early on, most of science thought the genetic material was protein —that changed in 1952

Deoxyribonucleic acid (DNA) is the genetic material, but early on, most of science thought the genetic material was protein. That changed in 1952.

Sometimes you gotta break a couple DNA strands to make a memory

Sometimes you gotta break a couple DNA strands to make a memory

Or at least that's what recent research into memory formation in mice suggests!

Oncology screening might be hitting its stride

Paid-members only

Oncology screening might be hitting its stride

One of the most important papers in the history of genetics was basically ignored when it was published in 1944

One of the most important papers in the history of genetics was basically ignored when it was published in 1944

When Oswald Avery, Colin Macleod and Maclyn McCarty published their paper in 1944 showing unequivocally that DNA was the genetic material, it wasn’t very well received.

The "most beautiful experiment in biology" was performed by Meselson and Stahl in 1957

The "most beautiful experiment in biology" was performed by Meselson and Stahl in 1957

Watson and Crick solved the structure of DNA and everyone lived happily ever after, right? Wrong. That was just the opening argument.

The discovery of the DNA double-helix was the culmination of decades of work from numerous contributors

The discovery of the DNA double-helix was the culmination of decades of work from numerous contributors

History is written by victors, and that statement couldn't be more true than it is in the case of Watson and Crick's 'discovery' of the DNA double helix.

Linus Pauling proposed a triple helical structure for DNA in 1953. Here's why he got it so wrong

Linus Pauling proposed a triple helical structure for DNA in 1953. Here's why he got it so wrong

The kaleidoscopic image below is the triple helix Linus Pauling proposed as the structure of DNA in February 1953. Here's why he got it so wrong:

$Did you know that there was a high quality diffraction of B-DNA made a year before Rosalind Franklin and Raymond Gosling generated photo 51?$

Did you know that there was a high quality diffraction of B-DNA made a year before Rosalind Franklin and Raymond Gosling generated photo 51?

Elwyn Beighton and William Astbury generated a nearly flawless diffraction of B-DNA in 1951, a full year ahead of Franklin and Gosling. They never shared or published it.

RavGen got Natera to cough up $57m. What's going on with non-invasive screening test IP?

Paid-members only

Start-Upomics Featured

RavGen got Natera to cough up $57m. What's going on with non-invasive screening test IP?

$Florence Bell and William Astbury's x-ray diffraction work on a 'pile of pennies'$

Florence Bell and William Astbury's x-ray diffraction work on a 'pile of pennies'

The first crystal structure of DNA was published in 1938. It was generated by Florence Bell, a scientist you need to know.

The story of Phoebus Levene, one of the mostly invisible grandfathers of nucleic acids

The story of Phoebus Levene, one of the mostly invisible grandfathers of nucleic acids

Watson and Crick were the first to describe the structure of the DNA double helix. Their major contribution to science was, at its core, a synthesis of all of the best data available at the time.

Pfizer developed a technique for determining the primary structure of their mRNA vaccine including detecting base modifications, the 5'-cap, and the poly-A tail

Pfizer developed a technique for determining the primary structure of their mRNA vaccine including detecting base modifications, the 5'-cap, and the poly-A tail

Pfizer developed a new method to determine the primary structure of RNA. 'So, they made a sequencer?' Kinda.

The story of the polymerase chain reaction and how sometimes timing is everything

The story of the polymerase chain reaction and how sometimes timing is everything

The method below has been cited more than 600,000 times and is one of the most important developments in the history of science.