DNA Nettie Stevens, a former school teacher turned geneticist, discovered sex chromosomes in 1905. Here's her story: Nettie Stevens’ contributions to the field of genetics were groundbreaking.
DNA The structure of the DNA double-helix was published in 1953, but it took another 13 years to actually crack the genetic code. The questions of how DNA is copied and codes for proteins remained for a while after the structure was confirmed.
DNA Chargaff’s Rule is the most basic rule of DNA A and T, and G and C are present in the same amounts in DNA. It’s the most basic rule of DNA. It’s also called Chargaff’s Rule.
DNA Deoxyribonucleic acid (DNA) is the genetic material, but early on, most of science thought the genetic material was protein —that changed in 1952 Deoxyribonucleic acid (DNA) is the genetic material, but early on, most of science thought the genetic material was protein. That changed in 1952.
DNA Sometimes you gotta break a couple DNA strands to make a memory Or at least that's what recent research into memory formation in mice suggests!
DNA One of the most important papers in the history of genetics was basically ignored when it was published in 1944 When Oswald Avery, Colin Macleod and Maclyn McCarty published their paper in 1944 showing unequivocally that DNA was the genetic material, it wasn’t very well received.
DNA The "most beautiful experiment in biology" was performed by Meselson and Stahl in 1957 Watson and Crick solved the structure of DNA and everyone lived happily ever after, right? Wrong. That was just the opening argument.
DNA The discovery of the DNA double-helix was the culmination of decades of work from numerous contributors History is written by victors, and that statement couldn't be more true than it is in the case of Watson and Crick's 'discovery' of the DNA double helix.
DNA Linus Pauling proposed a triple helical structure for DNA in 1953. Here's why he got it so wrong The kaleidoscopic image below is the triple helix Linus Pauling proposed as the structure of DNA in February 1953. Here's why he got it so wrong:
DNA Did you know that there was a high quality diffraction of B-DNA made a year before Rosalind Franklin and Raymond Gosling generated photo 51? Elwyn Beighton and William Astbury generated a nearly flawless diffraction of B-DNA in 1951, a full year ahead of Franklin and Gosling. They never shared or published it.
Paid-members only Start-Upomics Featured RavGen got Natera to cough up $57m. What's going on with non-invasive screening test IP?
DNA Florence Bell and William Astbury's x-ray diffraction work on a 'pile of pennies' The first crystal structure of DNA was published in 1938. It was generated by Florence Bell, a scientist you need to know.
DNA The story of Phoebus Levene, one of the mostly invisible grandfathers of nucleic acids Watson and Crick were the first to describe the structure of the DNA double helix. Their major contribution to science was, at its core, a synthesis of all of the best data available at the time.
DNA Pfizer developed a technique for determining the primary structure of their mRNA vaccine including detecting base modifications, the 5'-cap, and the poly-A tail Pfizer developed a new method to determine the primary structure of RNA. 'So, they made a sequencer?' Kinda.
DNA The story of the polymerase chain reaction and how sometimes timing is everything The method below has been cited more than 600,000 times and is one of the most important developments in the history of science.
DNA A multi-billion dollar industry was spawned from the discovery of circulating free DNA Two gels spawned a multi-billion dollar industry that didn't exist prior to their publication in 1997.
DNA FFPE is great for histology and terrible for molecular testing Formalin-fixed, paraffin-embedded (FFPE) tissues in oncology diagnostics: is there a better way?
DNA The story of Rosalind Franklin and photo 51 The most famous photo in the history of genetics wasn’t generated by Watson and Crick, but that didn’t stop them from using it to solve the structure of DNA!