Proteomics Sickle Cell Anemia was molecularly characterized in 1949 using a revolutionary new technique: electrophoresis Sickle Cell Anemia was the first inherited disease to be molecularly characterized. It was done in 1949 using a revolutionary new method: electrophoresis.
Proteomics Protein sequencing is the latest cutting edge technique in our proteomics toolkit Protein sequencing is the latest cutting edge technique in our proteomics toolkit. But when will it be ready for primetime?
Genomics The yeast used to brew Guinness is unlike any other found in Ireland or the UK The yeast used to make your most recent Guinness isn’t like any other found in Ireland or the UK!
Paid-members only Start-Upomics Featured Is the life sciences bankruptcy bloodbath waxing or waning? Let's hope Nanostring and Invitae aren't emblematic of what's to come!
Proteomics Mass Spec is leading the charge in bringing high-throughput proteomics to a lab near you Mass Spec: It's not just for chemistry nerds anymore.
Autoimmunity 80% of patients with an autoimmune disease are women, we are now beginning to understand why Approximately 80% of people with autoimmune diseases are women. We may now understand why this extreme gender bias exists.
Paid-members only Conferenceomics Featured There was a lot of 'omics sizzle at this years' AGBT, and I'm not talking about the wicked sun-burns
DNA The "most beautiful experiment in biology" was performed by Meselson and Stahl in 1957 Watson and Crick solved the structure of DNA and everyone lived happily ever after, right? Wrong. That was just the opening argument.
Paid-members only Illumina Featured Add open-source sequencers to the list of things short-read manufacturers have to deal with now
DNA The discovery of the DNA double-helix was the culmination of decades of work from numerous contributors History is written by victors, and that statement couldn't be more true than it is in the case of Watson and Crick's 'discovery' of the DNA double helix.
Proteomics There are lot's of cool new ways to measure the proteome! High throughput proteomics could revolutionize our understanding of human disease, but it's going to take some major innovations to get us there!
Proteomics Proteomics based MCEDs are coming in hot and will probably hit the market sooner than anyone thinks Proteomics is coming to the oncology market faster than any of you think. This paper shows why.
DNA Linus Pauling proposed a triple helical structure for DNA in 1953. Here's why he got it so wrong The kaleidoscopic image below is the triple helix Linus Pauling proposed as the structure of DNA in February 1953. Here's why he got it so wrong:
Proteomics The importance of taking out the trash: An overview of cellular protein degradation pathways The importance of taking out the trash: An overview of cellular protein degradation pathways.
Virology The evidence that Epstein-Barr Virus can cause multiple sclerosis is mounting It has been hypothesized that infection with Epstein-Barr Virus can result in the development of multiple sclerosis. We now have good evidence that this is true.
DNA Did you know that there was a high quality diffraction of B-DNA made a year before Rosalind Franklin and Raymond Gosling generated photo 51? Elwyn Beighton and William Astbury generated a nearly flawless diffraction of B-DNA in 1951, a full year ahead of Franklin and Gosling. They never shared or published it.
Proteomics The Proteome: It's a bit more complex than any of us would like Translating the Proteome: There’s more to making proteins than just transcribing DNA into mRNA.
Protein Sequencing Sequencing proteins with nanopores is hard. Engineered nanopores might make it a little easier. Nanopores, what can't they do? Well, they're not very good at sequencing proteins. Yet.
Paid-members only Start-Upomics Featured RavGen got Natera to cough up $57m. What's going on with non-invasive screening test IP?