Paid-members only Start-Upomics Tempus' good very bad week included a $410m IPO, a lawsuit and a ~$20 swing in their post-IPO stock price
Autoimmunity A new genetic cause for Inflammatory Bowel Disease has been discovered Inflammatory diseases affect 5% of the population but we have a poor understanding of how to treat them. Multi-omic studies are changing that.
Breakthroughs mRNA vaccines almost weren't a thing It is estimated that COVID-19 vaccination has prevented over 20 million deaths worldwide. We can thank the dogged perseverance of a browbeaten scientist for that.
Paid-members only High-Throughput Sequencing If you thought the sequencing wars were hot already, have you considered what a $10 genome might do to them?
Evolution Have you ever wanted a superpower? Me too! Some human populations have genes that would make even Poseidon jealous!
Metabolome Metabolomics: Hype or Heroine? How does the promise of metabolomics stack up against our current reality? It’s complicated.
DNA The 2-D structure of tRNA was solved in 1965, its solver probably isn't someone you've heard of before The next great mystery to solve after the discovery of the DNA double helix was to figure out how the nucleotide sequence coded for proteins.
Paid-members only Start-Upomics Who's prioritizing bringing the next generation of sequencing technology to the clinic? The answer might surprise you.
Laboratory Developed Tests Mice, Frogs, Rabbits, OH MY! The early days of pregnancy testing were wild. For the better part of 40 years, pregnancy tests were done by injecting urine into animals and seeing what happened. No, seriously!
Cancer Coming to a dermatologist near you: The microscope will see you now. We've heard a lot about liquid biopsies, but what if I told you non-invasive virtual ones are now a possibility?
Genetics The ends of our chromosomes are a paradox What if I told you that we didn't fully understand how human DNA was copied until 1989?
Tumor Microenvironments The tumor microenvironment is a complicated place full of contradictions Macrophages in lung cancer get their chance in the spatial omics spotlight.
Paid-members only High-Throughput Sequencing Another summer of sequencing is upon us. Whose sparkle will beguile the hearts of suitors and dazzle the eyes of onlookers?
Diagnostics APOE4: no longer just a risk factor for Alzheimer’s, it's a genetically distinct form of the disease! This genetic distinction bears the gift of new tools to predict onset and track disease progression.
Genetics Biologically female mammals have two X chromosomes, but what might surprise you is that one of those X's is turned off. We first discovered there was something funny going on with X-chromosomes in 1948.
Microbiomics Pangenomes: the coolest new thing in human genetics got its start in bacteria. No, seriously! Bacteria are complicated. We invented pangenomes to better understand them.
