Genetics 6LL3, better known as Dolly the Sheep, showed that mammalian cloning was possible in 1997 Why was a sheep the first choice for this ground-breaking work?
Epigenomics Epigenome editors are coming for cholesterol (and other diseases)! Ever heard of an ‘epigenome editor?’ Well, buckle up, because they could be the source of a long-term cure for high cholesterol!
Proteomics PROTACs and LYTACs: How therapeutics can take advantage of proteomic garbage men Cells are biological marvels, but even they need help taking out the trash sometimes.
DNA One of the most important papers in the history of genetics was basically ignored when it was published in 1944 When Oswald Avery, Colin Macleod and Maclyn McCarty published their paper in 1944 showing unequivocally that DNA was the genetic material, it wasn’t very well received.
Paid-members only Start-Upomics Featured Reports of NanoString's death appear to have been severely overstated
Genetics Beadle and Tatum were the first to marry biochemistry with genetics in 1941 The field of molecular biology was born in 1941 through the marriage of genetics and biochemistry.
Proteomics Resolving the proteome with single-cell and spatial proteomics. Single-cell and spatial proteomics: a more refined future.
Evolution Featured The story of how apes (and humans) lost their tails! How a ‘jumping gene’ caused apes (and humans) to quit monkeying around and ditch their tails.
Paid-members only Genomic Sequencing Featured Illumina ruffled some feathers this week with a video appeal to moderate sized "core labs"
Genomics RNA interference was a knockout discovery in 1998! One of the best ways to figure out what a gene does is to get rid of it and see what happens.
Proteomics Proteomics is a data deluge. Taming the firehose is still a work in progress. Once we have all of this amazing proteomic data, what do we do with it???
Microbiomics The establishment and maintenance of your microbiome is mostly a family affair, but be careful who you swap spit with! Being in close contact with other people is just human nature, so it makes sense that the bugs who colonize us also tend to colonize the people around us.
Paid-members only Start-Upomics Featured Francis deSouza is back from his post-Illumina purgatory with a new AI start-up
Proteomics Multiplex aptamer/antibody arrays are a gateway drug to get genetics people to embrace proteomics Multiplex Apater and Immuno Affinity Arrays are perfect for getting people excited about the power of proteins!
Proteomics Fred Sanger, the father of DNA sequencing, cut his teeth doing protein sequencing and snagged a Nobel in the process! Fred Sanger received a Nobel Prize for his work with Insulin. As the father of DNA sequencing, this surely was for insulin's nucleic acid sequence? It wasn't.
Genomic Sequencing The human genome sequence is finally (almost) totally complete. The pesky Y chromosome was the last hold-out! The human Y-chromosome has finally been fully sequenced! No, seriously this time, the genome is actually finished now, maybe.
Paid-members only Genomics Featured Complete Genomics wants America to give them a second chance. Should they?
Proteomics Sickle Cell Anemia was molecularly characterized in 1949 using a revolutionary new technique: electrophoresis Sickle Cell Anemia was the first inherited disease to be molecularly characterized. It was done in 1949 using a revolutionary new method: electrophoresis.
Proteomics Protein sequencing is the latest cutting edge technique in our proteomics toolkit Protein sequencing is the latest cutting edge technique in our proteomics toolkit. But when will it be ready for primetime?
Genomics The yeast used to brew Guinness is unlike any other found in Ireland or the UK The yeast used to make your most recent Guinness isn’t like any other found in Ireland or the UK!
Paid-members only Start-Upomics Featured Is the life sciences bankruptcy bloodbath waxing or waning? Let's hope Nanostring and Invitae aren't emblematic of what's to come!
