Complex genetic traits are getting taken to new heights The genetics of height gets the whole genome treatment
RNA Don't let highly expressed transcripts get the best of your RNA-seq dataset Whole transcriptome sequencing AKA RNA-seq: The good, the bad, the dynamic range?
DNA Solving the structure of the DNA double-helix took a village History is written by victors, and that statement couldn't be more true than it is in the case of Watson and Crick's 'discovery' of the DNA double helix.
Paid-members only Genomic Sequencing After 13 years, Illumina's 'little sequencer that could' has been replaced by a bigger, faster sibling
Bacteria are better at math than I am Large Language Models have gotten all the AI buzz lately, but did you know that bacterial neural networks can solve computational problems now?
Transcriptomics Transcriptomes are sometimes more useful than 'whole genomes' Transcriptomes: under-appreciated, underutilized, and sometimes more useful than WGS.
DNA Linus Pauling and his DNA triple helix Linus Pauling proposed a triple helix as the structure of DNA in February 1953. Here's why he got it so wrong.
Paid-members only Start-Upomics Let's Get Checked buys TruePill to take on end-to-end at home healthcare
DNA Beighton and Astbury beat Gosling and Franklin to a pristine diffraction of DNA. They never shared it Elwyn Beighton and William Astbury generated a nearly flawless diffraction of B-DNA in 1951, a full year ahead of Franklin and Gosling. They never shared or published it.
Genetics Ethnic Stratification: Sounds complicated, but in genomics it helps everyone Ethnic stratification and why single reference based analysis methods aren't 'good enough.'
Precision Medicine MILTON is here to help predict 1,000 diseases before they happen Multi-omics can predict diseases now, kinda
Paid-members only Start-Upomics Guardant Co-CEO's million dollar bet roils patients, employees and anyone with two functioning brain cells
Genetics A genetic investigation into the 'population collapse' at Easter Island What caused the 'collapse' of the Rapanui population on Easter Island? Genetics is now setting the record straight.
Genomics Pangenomes are here to bring equity to genomics Reference genomes: what they are and why the next big thing in genomics is the human pangenome.
DNA The structure of DNA proposed by William Astbury and Florence Bell in 1938 The first 3D structure of DNA was published in 1938. It was generated by Florence Bell, a scientist you need to know.
Paid-members only Genetic Screening Australia just banned the life insurance industry from using genetic testing; America should too
Genetics The genetics of child sacrifice at Chichén Itzá Ritual human sacrifice was an important part of ancient Mayan life and now genetics is helping us to identify the origins of those who were sacrificed.
High-Throughput Sequencing Checking your metrics is an important piece of the sequencing process High throughput sequencing metrics: Don't be a monster, review them before sending data to the triage team.
DNA Phoebus Levene and the discovery of the 2-dimensional structure of DNA Watson and Crick were the first to describe the structure of the DNA double helix. Their major contribution to science was, at its core, a synthesis of all of the best data available at the time.