Paid-members only High-Throughput Sequencing Another summer of sequencing is upon us. Whose sparkle will beguile the hearts of suitors and dazzle the eyes of onlookers?
Diagnostics APOE4: no longer just a risk factor for Alzheimer’s, it's a genetically distinct form of the disease! This genetic distinction bears the gift of new tools to predict onset and track disease progression.
Genetics Biologically female mammals have two X chromosomes, but what might surprise you is that one of those X's is turned off. We first discovered there was something funny going on with X-chromosomes in 1948.
Microbiomics Pangenomes: the coolest new thing in human genetics got its start in bacteria. No, seriously! Bacteria are complicated. We invented pangenomes to better understand them.
Paid-members only Hype Cycles AlphaFold, the second coming of Christ or just another useful tool in the life sciences?
Multi-Omics Genetic Determinism: What it is and how we can avoid it with multi-omics One thing we constantly battle in genomics is, “What does it all mean?”
Therapeutics Are personalized vaccines the next big thing in cancer therapy? The figure kind of speaks for itself.
Breakthroughs Insulin: It was believed to exist, but everyone who tried to isolate it failed The path to insulin isolation was anything but straight.
Paid-members only Genomic Sequencing Spatial omics (and other creative applications) might give that dying NovaSeq of yours a second life!
DNA Nettie Stevens, a former school teacher turned geneticist, discovered sex chromosomes in 1905. Here's her story: Nettie Stevens’ contributions to the field of genetics were groundbreaking.
Microbiomics We’ve known since the time of Pavlov that there’s a connection between our gut and brain; now we know our microbiomes play a role in that game of telephone too! The gut-brain axis: now with microbes!
RNA That beating sensation you feel in your chest is the product of billions of cells working together to pump blood throughout your body. Ever get lost in your own heart? Have no fear, there's a new atlas for that!
Microbiomics Pathobionts: The opportunists hiding in our microbiomes The microbes we co-exist with can be friends, foes, or just along for the ride. They can also switch between being all of those things…
Genetics Barbara McClintock discovered a little thing called the transposable element in 1950 While everyone else was distracted by the structure of DNA, Barbara McClintock was discovering a little thing called the transposable element.
Paid-members only Genetics What happens if insurance companies start using your genetic data against you?
Genomics The evolutionary history of coffee is probably more complicated than you think That dark and delicious brew billowing clouds of irresistible coffee incense next to you is most likely the product of Coffea arabica.
Microbiomics Clinical applications of the microbiome are still very much a work in progress What's the clinical usefulness of a microbiome? We’re still trying to figure that part out!
Genetics The first human "Mendelian" disease was described in 1902 Mendel first described his laws of genetic inheritance in 1865. They were promptly ignored for 35 years.
