Paid-members only Omics One of the most underappreciated techniques in Omics is Hi-C. That needs to change
RNA Bridge RNAs are here to take CRISPR's crown Move over CRISPR, bridge RNAs are here to make the precision genome edits that you can't.
Fecal Matters The messiest part of Omics? Dealing with all the different sample types The good, the bad, the...uhhh: Everything you ever wanted to know about all the different Omics sample types!
High-Throughput Sequencing In 2009, high throughput sequencing gave us our first glimpse of the 3-D organization of the DNA in our nuclei While chromosomes are usually depicted as X's, they actually spend most of their time jumbled up like a giant ball of yarn.
Evolution Why do women live longer than men? Sperm production is expensive Are you a guy? Do you want to live longer? It might be time to ditch your sperm.
Genetics Genealogy databases aren't just for finding your relatives anymore The killer app for consumer genetics literally is to catch killers. Here's why:
Genetics The 'Histone Code' fundamentally changed how we think about gene expression Histones were once thought to just be dumb structural proteins that held chromatin together; now we know that the ‘histone code’ is a major regulator of gene expression.
Paid-members only Start-Upomics Tempus' good very bad week included a $410m IPO, a lawsuit and a ~$20 swing in their post-IPO stock price
Autoimmunity A new genetic cause for Inflammatory Bowel Disease has been discovered Inflammatory diseases affect 5% of the population but we have a poor understanding of how to treat them. Multi-omic studies are changing that.
Breakthroughs mRNA vaccines almost weren't a thing It is estimated that COVID-19 vaccination has prevented over 20 million deaths worldwide. We can thank the dogged perseverance of a browbeaten scientist for that.
Paid-members only High-Throughput Sequencing If you thought the sequencing wars were hot already, have you considered what a $10 genome might do to them?
Evolution Have you ever wanted a superpower? Me too! Some human populations have genes that would make even Poseidon jealous!
Metabolome Metabolomics: Hype or Heroine? How does the promise of metabolomics stack up against our current reality? It’s complicated.
DNA The 2-D structure of tRNA was solved in 1965, its solver probably isn't someone you've heard of before The next great mystery to solve after the discovery of the DNA double helix was to figure out how the nucleotide sequence coded for proteins.
Paid-members only Start-Upomics Who's prioritizing bringing the next generation of sequencing technology to the clinic? The answer might surprise you.
Laboratory Developed Tests Mice, Frogs, Rabbits, OH MY! The early days of pregnancy testing were wild. For the better part of 40 years, pregnancy tests were done by injecting urine into animals and seeing what happened. No, seriously!
Cancer Coming to a dermatologist near you: The microscope will see you now. We've heard a lot about liquid biopsies, but what if I told you non-invasive virtual ones are now a possibility?