Paid-members only CRISPR CRISPR isn't the only relevant genome engineering technique, can we talk about the others too, please?
High-Throughput Sequencing Let the Nanopore Wars begin: BGI has a new nanopore sequencer The Nanopore Wars are coming and BGI just fired the first salvo in what is sure to be an exciting conflict
Genetic Screening Low frequency variants are hard to detect, but don't let that stop you from implying you can catch them all Detecting variants can be challenging, especially detecting the ones that aren't very abundant.
PCR Who discovered PCR first? The answer might surprise you The method below has been cited more than 600,000 times and is one of the most important developments in the history of science.
The Shingles vaccine does more than protect you from shingles Vaccines have gotten a lot of press lately. Did you know there's evidence the Shingles one can also help prevent dementia?
Genomic Sequencing Son of a Bias, why does my sequencing dataset look like trash? High throughput sequencing: Biases and how they can get the best of you and your data
DNA I sometimes give Illumina a hard time, but they've commercialized some killer products Illumina is considered by many to have single handedly transformed the field of genomics. They did it by building on the foundation Solexa established in 1997.
Paid-members only Start-Upomics Illumina recently courted investors with a presentation on how their new product R&D pipeline is going to resurrect the Illumina stock price
Genetics Would you like some Hi-C with that Woolly Mammoth? Woolly Mammoths were just big, furry, elephants, right? Maybe, and now we have the tools to compare the structures of their genomes.
High-Throughput Sequencing Q-scores, what they mean, and why sometimes bigger isn't necessary High throughput sequencing metrics: Q-scores, what are they good for?
DNA Rosalind Franklin's legacy goes well beyond her work on the structure of DNA The most famous photo in the history of genetics wasn’t generated by Watson and Crick, but that didn’t stop them from using it to solve the structure of DNA.
Therapeutics Need to reset your brain? It might be time to go on a trip Mr. Mackey always told us that, “Drugs are bad.” But sometimes they’re just misunderstood.
High-Throughput Sequencing Being accurate about sequencing accuracy High throughput sequencing metrics: Let’s be accurate about accuracy.
Prenatal Testing Circulating cell free DNA testing was born in 1997 The two gels above spawned a multi-billion dollar industry that didn't exist prior to their publication in 1997.
Paid-members only Genomic Sequencing Oxford Nanopore says that the short-read vs long-read conversation is pointless because they can do both
DNA Featured What came first, DNA methylation or the variant? DNA sequence variants can change more than just the properties of the proteins that genes code for, they can also change what proteins get expressed!
Genomic Sequencing Everything you ever wanted to know about cluster based and single-molecule sequencing Clusters vs single molecules in DNA sequencing: Here’s the short and the long of it.
Breakthroughs Contrary to popular belief, there are 21 amino acids and the 21st was discovered in 1976 You might have been told that there are 20 amino acids. That’s a lie.
