Brian Krueger

Transcriptomics

Put on your dive gear: we're going deep on single-cell and spatial transcriptomics methods!

A not-so-deep dive into Single Cell and Spatial Transcriptomics

Historical Paper Review

Linus Pauling molecularly characterized the first Mendelian Disease: Sickle Cell Anemia

Sickle Cell Anemia was the first inherited disease to be molecularly characterized. It was done in 1949 using a revolutionary new method: electrophoresis.

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Weekly Reading List

Weekly Reading List: Nov 4, 2024

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November 4, 2024 Hey There! Thanks for spending part of your week with Omic.ly! This Week's Headlines 1) A USB drive? Nah, an epigenetic drive! 2) A not-so-deep dive into Single Cell and Spatial Transcriptomics 3) Linus Pauling molecularly characterized the first Mendelian Disease: Sickle Cell Anemia

Longevity

Cutting calories extends life, but not for the reasons you might think

Would you cut 40% of your caloric intake if it meant you'd live 40% longer?

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Molecular Testing

At-home testing companies were put on notice with FDA's most recent warning letter to Molecular Testing Labs

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October 28, 2024 Hey There! Thanks for spending part of your week with Omic.ly! This Week's Headlines 1) Cutting calories extends life, but not for the reasons you might think 2) Single-cell and Spatial Transcriptomics: All the cool kids are doing it 3) The most beautiful experiment

DNA

The most beautiful experiment in biology

Watson and Crick solved the structure of DNA and everyone lived happily ever after, right? Wrong. That was just the opening argument.

Transcriptomics

Single-cell and Spatial Transcriptomics: All the cool kids are doing it

Single-cell and spatial transcriptomics: What you need to know!

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Weekly Reading List

Weekly Reading List: Oct 28, 2024

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Exomes

Element Bioscience makes a big bet on rapid exome sequencing

Complex genetic traits are getting taken to new heights

The genetics of height gets the whole genome treatment

RNA

Don't let highly expressed transcripts get the best of your RNA-seq dataset

Whole transcriptome sequencing AKA RNA-seq: The good, the bad, the dynamic range?

DNA

Solving the structure of the DNA double-helix took a village

History is written by victors, and that statement couldn't be more true than it is in the case of Watson and Crick's 'discovery' of the DNA double helix.

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Weekly Reading List

Weekly Reading List: October 21, 2024

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October 21, 2024 Hey There! Thanks for spending part of your week with Omic.ly! Maybe we'll just switch to Monday mornings for the newsletter to post... My weeks and weekends have been a bit of a hurricane themselves lately but hopefully I can get back to the

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Genomic Sequencing

After 13 years, Illumina's 'little sequencer that could' has been replaced by a bigger, faster sibling

Bacteria are better at math than I am

Large Language Models have gotten all the AI buzz lately, but did you know that bacterial neural networks can solve computational problems now?

Transcriptomics

Transcriptomes are sometimes more useful than 'whole genomes'

Transcriptomes: under-appreciated, underutilized, and sometimes more useful than WGS.