Omic.ly Weekly 53 December 9, 2024 Hey There! Thanks for spending part of your week with Omic.ly! This Week's Headlines 1) Foundation models are all the rage today - Now there's one for genomes! 2) Epigenetics! You've heard of it, but what do you know about
Paid-members only FDA Just when you thought you might be safe, FDA sticks its nose into MRD testing (again)
Artificial Intelligence RhoFold+: A large language model for RNA structure prediction Can LLMs predict RNA structures?
RNA Direct RNA sequencing might tell us about more than just the bases Post-transcriptional modifications: Why sequencing RNA directly is the future of transcriptomics
Historical Paper Review Oswald Avery, Colin Macleod and Maclyn McCarty showed that DNA was the genetic material in 1944 One of the most important papers in the history of genetics was basically ignored when it was published in 1944.
Omic.ly Weekly 52 December 2, 2024 Hey There! Thanks for spending part of your week with Omic.ly! It's officially the 1 year-a-versary of this newsletter! Thanks to all of you who have stuck it out for every issue (That's like 2 of you)! This Week's Headlines
Paid-members only How might the election change how FDA approaches enforcement of their new LDT rule?
Diagnostics Metagenomics hits the clinic to diagnose CNS infections Whole genome metagenomics is better than the standard of care in detecting the causal bugs of CNS infections
Transcriptomics Transcriptomics is better with long-reads Spoiler Alert: The holy grail of transcriptomics is long-reads.
Molecular Biology Molecular Biology is the offspring of biochemistry and genetics The field of molecular biology was born in 1941 through the marriage of genetics and biochemistry.
Omic.ly Weekly 51 November 25, 2024 Hey There! Thanks for spending part of your week with Omic.ly! But before we get to this week's juicy bits, I wanted to let you know that this is now a two blog household! My wife who is an epidemiologist and who spent her
Nanopores Nanopores are getting on the rapid NICU/PICU sequencing bandwagon Nanopores take on rapid neonatal sequencing
Transcriptomics New tech always has risks and limitations, single-cell and spatial transcriptomics are no exception Single-Cell and Spatial Transcriptomics: Risks, Limitations, and Questions to Ask
Historical Paper Review A wormy discovery becomes a knockout laboratory technique One of the best ways to figure out what a gene does is to get rid of it and see what happens.