Brian Krueger

DNA

The discovery of the DNA double-helix was the culmination of decades of work from numerous contributors

History is written by victors, and that statement couldn't be more true than it is in the case of Watson and Crick's 'discovery' of the DNA double helix.

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February 4th, 2024 Hey There! Thanks for spending part of your Sunday with Omicly! This week's headlines include: 1) Proteomics based MCEDs are coming in hot and will probably hit the market sooner than anyone thinks. 2) There are lot's of cool new ways to measure

Proteomics

There are lot's of cool new ways to measure the proteome!

High throughput proteomics could revolutionize our understanding of human disease, but it's going to take some major innovations to get us there!

Proteomics

Proteomics based MCEDs are coming in hot and will probably hit the market sooner than anyone thinks

Proteomics is coming to the oncology market faster than any of you think. This paper shows why.

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January 28th, 2024 Hey There! Thanks for spending part of your Sunday with Omicly! This week's headlines include: 1) The evidence that Epstein-Barr Virus can cause multiple sclerosis is mounting 2) The importance of taking out the trash: An overview of cellular protein degradation pathways. 3) Linus Pauling

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Weekly Reading List

Weekly Reading List: Jan 28, 2024

DNA

Linus Pauling proposed a triple helical structure for DNA in 1953. Here's why he got it so wrong

The kaleidoscopic image below is the triple helix Linus Pauling proposed as the structure of DNA in February 1953. Here's why he got it so wrong:

Proteomics

The importance of taking out the trash: An overview of cellular protein degradation pathways

The importance of taking out the trash: An overview of cellular protein degradation pathways.

Virology

The evidence that Epstein-Barr Virus can cause multiple sclerosis is mounting

It has been hypothesized that infection with Epstein-Barr Virus can result in the development of multiple sclerosis. We now have good evidence that this is true.

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Illumina Featured

Is spatial-omics the new sequencing land-grab?

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January 21, 2024 Hey There! Thanks for spending part of your Sunday with Omicly! This week's headlines include: 1) Sequencing proteins with nanopores is hard. Engineered nanopores might make it a little easier. 2) The Proteome: It's a bit more complex than any of us would

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Weekly Reading List

Weekly Reading List: Jan 21, 2024

DNA

Did you know that there was a high quality diffraction of B-DNA made a year before Rosalind Franklin and Raymond Gosling generated photo 51?

Elwyn Beighton and William Astbury generated a nearly flawless diffraction of B-DNA in 1951, a full year ahead of Franklin and Gosling. They never shared or published it.

Proteomics

The Proteome: It's a bit more complex than any of us would like

Translating the Proteome: There’s more to making proteins than just transcribing DNA into mRNA.

Protein Sequencing

Sequencing proteins with nanopores is hard. Engineered nanopores might make it a little easier.

Nanopores, what can't they do? Well, they're not very good at sequencing proteins. Yet.

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Start-Upomics Featured

RavGen got Natera to cough up $57m. What's going on with non-invasive screening test IP?

DNA

Florence Bell and William Astbury's x-ray diffraction work on a 'pile of pennies'

The first crystal structure of DNA was published in 1938. It was generated by Florence Bell, a scientist you need to know.

Proteomics

The Proteome: It's a bit more complex than any of us would like

Proteoforms: This is where things start to get complicated.

Epigenomics

The epigenome's role in aging gets some mechanistic answers

Feeling old? It might be time to blame your epigenome.