Omic.ly Weekly 37 August 11, 2024 Hey There! Thanks for spending part of your Sunday with Omic.ly! I'll be on vacation from the 13th to the 25th. Unfortunately, edition 39 might be delayed until Tuesday the 27th, so don't be too worried if you don't get
Paid-members only Start-Upomics The 23andMe board tells Anne Wojcicki to do better in her attempt to take 23andMe private after a rocky 3 years as a public company
Genetics If only Ponce de Leon had known about IL-11 Who knew that the fountain of youth was as simple as blocking inflammatory signaling through IL-11?
Genomics Why short-read sequencing can't ever get us a 'whole genome' Short-reads miss things, or: How I learned to stop worrying and love the long-read.
Genomic Sequencing Frederick Sanger sequenced the first DNA genome, he didn't use 'Sanger Sequencing' to do it Frederick Sanger invented a famous DNA sequencing method. It's not the one pictured below (which he also invented).
Omic.ly Weekly 36 August 4, 2024 Hey There! Thanks for spending part of your Sunday with Omic.ly! This Week's Headlines 1) If only Ponce de Leon had known about IL-11 2) Why short-read sequencing can't ever get us a 'whole genome' 3) Frederick Sanger sequenced the
Therapeutics How does the brain cause headaches if it can't feel pain? Do you suffer from migraines? We might have some new clues about how they happen.
Genomic Sequencing Counting the things short-reads are good for What's the point of short-reads if long-reads do basically everything in genomics better? There are five, FIVE, *thunderclap*, applications where short reads excel, ah, ah, ah!
Proteins Green Fluorescent Protein was first discovered in Jellyfish in 1960 In 1994, an obscure jellyfish protein was stuck into a worm. It has enlightened biology and medicine ever since.
Omic.ly Weekly 35 July 28, 2024 Hey There! Thanks for spending part of your Sunday with Omic.ly! This Week's Headlines 1) How does the brain cause headaches if it can't feel pain? 2) Counting the things short-reads are good for 3) Green Fluorescent Protein was first discovered in
Paid-members only Protein Sequencing There are a lot of companies working on protein sequencing, so who is in the lead?
Protein Sequencing Reverse Translation doesn't exist in nature, but that's not stopping us from trying to do it! There are few things deserving of the superlative ‘holy grail,’ but Reverse Translation is one of them.
Diagnostics Assay failures are common in the clinical lab, here are 5 of my favorites. Troubleshooting assay failures is a second full-time job in R&D. Here are my top 5 'favorite' root causes!
DNA The Lac Operon: Everyone's heard of it, but do you know how it was discovered? 'If gene expression determines the function of a cell, it must be important to control that process?' Yes, very! Let me tell you about the PaJaMo experiment.
